Jeff began his scientific training at his mother's knee, coming with her to graduate classes and fieldwork as she pursued a Ph.D. in Ecology during the 1980s.  He attended the Bronx High School of Science, and then State University of New York at Binghamton where he graduated Suma Cum Laude with a B.S. in Biochemistry.  Throughout this time, Jeff spent his summers in molecular biology labs, interning at Mount Sinai School of Medicine, City College of New York, Hoffman-La Roche, and Columbia University School of Medicine.  Jeff started formal medical training at NYU School of Medicine as a part of the Medical Scientist Training Program, graduating in 2003 with an M.D. and Ph.D. in Basic Medical Sciences.  Medical training continued with an Internal Medicine residency at Mount Sinai School of Medicine and a Pulmonary and Critical Care Medicine Fellowship at Harvard Medical School.   During fellowship, he received post-doctoral training under Dr. Augustine M. K. Choi, which led to a formative observation that liver autophagy has a circadian rhythm in vivo.  With his mentor’s encouragement, Jeff set out to chart a nascent area: how circadian rhythms impact the molecular pathogenesis of diseases relevant to pulmonary and critical care medicine.   This interest has taken Jeff from Harvard to Washinton University School of Medicine where he set up a laboratory in 2014 to understand how circadian biology relates to respiratory disease.  The ark of his independent scientific career spans the fundamental molecular biology of lung circadian rhythms to clinically applying biological rhythms to optimize COVID-19 vaccine effectiveness.  Clinically, Jeff is an ICU intensivist and, in this capacity, was a front-line responder during the COVID-19 pandemic from 2020-2021.  During this time Jeff’s lab efforts were curtailed, but scholarship continued by employing clinical data to understand the viral drivers of asthma biological rhythms.