Dr. Bekelman’s research focuses on health care delivery, payment reform and cancer care transformation, integrating methods from the fields of innovation, epidemiology, clinical trials, behavioral and health economics and public policy. Dr. Bekelman has defined conceptual approaches to comparative effectiveness research in oncology and conducts pragmatic randomized and non-randomized, quasi-experimental studies of advanced cancer treatments and services to improve the length and quality of life for patients with cancer. His research has shown the survival benefits to treating aggressive cancer in the elderly, identified low-value cancer care and ineffective, resource-intense services at the end-of-life, and revealed new knowledge characterizing both potent and weak effects of clinician incentives to increase high-value cancer care.