Photo: Mark Roberts Looney, MD
Mark Roberts Looney, MD
Year elected: 2013
Current membership category: Active
University of California, San Francisco
513 Parnassus Avenue
HSE 1355A
Box 0130
San Francisco, CA 94143-0130
United States of America
Phone: 415-476-9563
Facsimile: 415-502-2605

Biographical statement

The main interest of Dr. Looney’s laboratory is the investigation of novel disease mechanisms that contribute to the pathogenesis of acute lung injury. His research group has identified that platelets, which are underappreciated as inflammatory cells, are intricately involved in the innate immune response in lung injury. Platelets are capable of synergizing with neutrophils to promote lung damage, and his laboratory has identified that platelets are therapeutic targets. His group has also identified that activated platelets can trigger the formation of neutrophil extracellular traps, or NETs, which are damaging to lung tissue and pathogenic in a transfusion-related acute lung injury model developed by his laboratory. Finally, a major area of study is the application of live lung imaging to visualize in real-time immune events at the alveolar-capillary interface that contribute to lung injury.

Institutional affiliations

University of California, San Francisco, School of Medicine (Primary)
Suneil K. Koliwad, MD, PhD is the representative at this institution.

Specialties

Critical Care Medicine
Pulmonology