Dr. Magee is the Elizabeth H. and James S. McDonnell III Professor of Pediatric Hematology/Oncology at Washington University School of Medicine. He trained as an undergraduate at the University of Wisconsin-Madison. He conducted research into body patterning mechanisms in Drosophila melanogaster in the laboratory of Sean Carroll (HHMI investigator) and contributed to two papers, including a Nature article. He then trained as an MD/PhD student at Washington University School of Medicine. He conducted his thesis work with Jeffrey Milbrandt (Chair of Genetics). He published several first author papers, including a seminal paper in Cancer Cell that described how haploinsufficiency at tumor suppressor loci can convey fully penetrant changes in cell identity at the level of individual cells. He received several awards for his research, including the Olin Medical Science Fellowship and the David M. Kipnis award. Dr. Magee then trained as a Pediatrics resident and Pediatric Hematology/Oncology fellow at the University of Michigan. He conducted his postdoctoral work with Dr. Sean Morrison (HHMI investigator, NAS member) at University of Michigan and then UT-Southwestern Medical Center. He published multiple papers, including a Cell Stem Cell paper that described age-specific consequences of leukemogenic PTEN mutations. That research formed the basis for Dr. Magee’s independent career, which has focused heavily on childhood-specific mechanisms of leukemia initiation and progression. Dr. Magee joined the Washington University faculty in 2013 and has been incredibly productive, both from a publications and funding standpoint. He has published seminal papers on mechanisms underlying hematopoietic stem cell ontogeny and their effects on leukemia initiation. He has become a leader in the field of myeloid biology and childhood leukemias. He is the founding scientific director of the McDonnell Pediatric Cancer Center at Washington University, a $22 million initiative to advance innovative therapies for pediatric cancer.