Photo: Jose Carlos Florez, MD, PhD
Jose Carlos Florez, MD, PhD
Year elected: 2014
Current membership category: Active
Massachusetts General Hospital
CPZN 5.250 – 185 Cambridge Street
Boston, MA 02114
United States of America
Phone: 617-643-3308
Facsimile: 617-643-6630

Biographical statement

Jose C. Florez is an Assistant Physician in Medicine at Massachusetts General Hospital (MGH), an Associate Professor at Harvard Medical School, and an Associate Member at the Broad Institute, where he is active in the Program in Medical and Population Genetics and the Broad Metabolism Initiative. His research program is centered on gene discovery for metabolic phenotypes, the physiological characterization of their mechanism of action, and modes of clinical translation. He and his group have contributed to the performance and analysis of genome-wide association studies in type 2 diabetes and related traits, in the Diabetes Genetics Initiative (formed by the Broad Institute, Lund University, and Novartis), the Framingham Heart Study, and other international consortia, such as MAGIC, GENIE, DIAGRAM, and SIGMA. He leads the genetic research efforts of the Diabetes Prevention Program, where the effects of genetic variants on diabetes incidence can be examined prospectively and their impact on specific behavioral and pharmacological preventive interventions can be assessed. He is the Principal Investigator of the Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR MGH) and also conducts other pharmacogenetic studies at MGH. He is clinically active in the MGH Diabetes Center, the Endocrine inpatient consult service, and the Down Syndrome Program. He is the recipient of the 2010 Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their independent research careers.

Institutional affiliations

Harvard Medical School, Massachusetts General Hospital (Primary)
Dennis A. Ausiello, MD is the representative at this institution.


Internal Medicine