The Journal of Clinical Investigation

Publications in the last 3 months by ASCI-member corresponding authors:

Pharmacokinetics and pharmacodynamics of a long-acting monoclonal antibody against malaria in African adults
Tuan M. Tran, Zonghui Hu, Kassoum Kayentao, Aissata Ongoiba, Sam Jones, Nada Abla, Sara A. Healy, Hamidou Cisse, Bickey H. Chang, Jeff Skinner, Leonid Serebryannyy, Sandeep R. Narpala, Robin Schlesinger, Kwang Huei Low, Rachel Kazmierski, Bob C. Lin, Joana Dias, Safiatou Doumbo, Didier Doumtabe, Anne C. Preston, Shanping Li, Mary E. Peterson, Amit Oberai, Adam D. Shandling, Joseph J. Campo, Sean C Murphy, Shinyi Telscher, Emily E. Coates, Edmund V. Capparelli, Amagana Dolo, Boubacar Traore, Robert A. Seder, Peter D. Crompton ASCI
Fate-mapping infiltrating monocytes following experimental myocardial infarction reveals differentiation trajectories in the infarcted heart
Andrew L. Koenig, Farid F. Kadyrov, Junedh M. Amrute, Steven Yang, Carla J. Weinheimer, Jessica M. Nigro, Attila Kovacs, Wenjun Li, Gabriella B. Smith, Lance Yeh, Daniel Kreisel, Kory J. Lavine ASCI
Human monoclonal antibodies targeting α-Gal restrict IgE engagement of α-Gal syndrome allergens
Hyeseon Cho, Youngsil Seo, Haewon Sohn, Shailesh K. Choudhary, Jeff Skinner, Ming Zhao, Ludmila Krymskaya, Weizhi Zhong, Justin Lack, Shanping Li, Boubacar Traore, Joshua Tan, Scott P. Commins, Peter D. Crompton ASCI
Bradykinin contributes to vasogenic edema in murine experimental cerebral malaria
Alessandro S. de Sa Pinheiro, Douglas E. Teixeira, Rodrigo P. Silva-Aguiar, Young Jun Shim, Alona A. Merkulova, Sadiq Silbak, Yelenna Skomorovska-Prokvolit, David Midem, Sidney Ogolla, Bjoern B. Burckhardt, Tanja Gangnus, Julio Scharfstein, Celso Caruso-Neves, Owen J.T. McCarty, David Gailani, Michael Bader, Philip J. Rosenthal, Arlene E. Dent, Chris J. Janse, Keith R. McCrae, Ana Acacia de Sa Pinheiro, James W. Kazura, Alvin H. Schmaier ASCI
Integrating transposable elements into blood gene regulatory networks reveals connectivity loss for schizophrenia genes
Helena Reyes-Gopar, Matthew L Bendall, Rodrigo R. R. Duarte, Timothy R Powell, Douglas F. Nixon ASCI
Dietary omega-6 lipids promote postinjury aberrant bone formation in obesity
Stefanie L. Moye, Monisha Mittal, Tarun Srinivasan, Sneha Korlakunta, Chase A. Pagani, Ayelet Dar, Oromo Geshow, Dylan Feist, Lauren G. Zacharias, Zhao Li, Aaron W. James, Gerta Hoxhaj, Andrew M. Smith, Katherine A. Gallagher, Thomas P. Mathews, Robert J. Tower, Benjamin Levi ASCI
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2
Rong Tian ASCI , E. Douglas Lewandowski
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. Reply.
Chai-Wan Kim, Matthew A. Mitsche, Jay D. Horton ASCI
Proteasome mutations associated with CANDLE syndrome cause altered neuronal development by dysregulating polyamine synthesis
Clayton W. Winkler, Benjamin Schwarz, Katie Williams, Sara Alehashemi, Simote T. Foliaki, Joseph Snow, Lisa Joseph, Audrey Thurm, Christopher L. Friend, Gwendolyn Cooper, Eric Bohrnsen, Farzana Bhuyan, Nathan T. Brandes, Ruin Moaddel, Manfred Boehm, Guibin Chen, Cole D. Kimzey, Bibiana Bielekova, Joanna Kocot, Peter Kosa, Cathryn L. Haigh, Raphaela Goldbach-Mansky ASCI , Karin E. Peterson
Genomic characterization of therapy-associated polyposis reveals an alkylating mutational signature from prior treatment
Yashika Parashar, Zsofia Sztupinszki, Aurel György Prósz, Xiaolu Wang, Pratyusha Bala, Shweta Kiran Cavale, Chinedu Ukaegbu, Sapna Syngal, Asaf Maoz, Leah H. Biller, Ramona Lim, Matthew B. Yurgelun, Zoltan Szallasi, Nilay S. Sethi ASCI
Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors
Guangfeng Wang, Dana C. Borcherding, Jiawan Wang, Xiaochun Zhang, Liuzhan Yang, Gorkem Oztosun, James J. Sears, Kangwen Xiao, Belinda B. Garana, Mark I. Zoberi, Aaron U. Bektas, Jeffrey J. Szymanski, Richa Rathore, Silvia Coma, Jonathan A. Pachter, Sara J.C. Gosline, Christine A. Pratilas, Angela C. Hirbe ASCI
Plasma nucleosome profiling reports on tumor burden and molecular subtypes in small cell lung cancer
Gavriel Fialkoff, Nobuyuki Takahashi, Israa Sharkia, Jenia Gutin, Nadav Hermoni, Michael Nirula, Rajesh Kumar, Lorinc Pongor, Samantha Nichols, Linda Sciuto, Kanak Parmar, Parth A Desai, Priyadarshini Suresh, Melissa L Abel, Rajaa El Meskini, Myriam Maoz, Yakir Rottenberg, Shoshan Nevo, Hovav Nechushtan, Tamar Peretz, Diana Roame, Ayala Hubert, Jonathan E. Cohen, Azzam Salah, Mark Temper, Albert Grinshpun, Zoe Weaver Ohler, Arun Rajan, William D Figg, Aviad Zick, Ronen Sadeh, Nir Friedman, Anish Thomas ASCI
Neuropeptide Y deficiency perturbs L-type calcium and outward potassium currents leading to ventricular arrhythmogenesis in mice
Seyi E. Elasoru, Christian Miccile, Jingwu Pan, Zhaoyang Zhang, Kalyanam Shivkumar, Herbert Herzog, Robert D. Harvey, Zhilin Qu, Olujimi A. Ajijola ASCI
HIF-1–mediated PPME1 expression promotes breast cancer progression via AKT activation and β-catenin recruitment
Yajing Lyu, Varen Talwar, Yongkang Yang, Si-Sim Kang, Shuyi Li, Shaima Salman, Daiana Drehmer, Yufeng Wang, Chelsey Chen, Vijay Ramu, Sujin Kim, Dylan Park, Tina Yi-Ting Huang, Emmanuel Datan, Dominic Dordai, Jonathan P. Schneck, Gregg L. Semenza ASCI
Rheumatoid factor production is genetically and molecularly distinct from rheumatoid arthritis
Mehmet Hocaoglu, Amr H. Sawalha ASCI
Assessing clinical relevance of off-target effects observed at suprapharmacological concentrations of SGLT2 inhibitors
Simeon I. Taylor ASCI
Enhancing gemcitabine uptake by promoting dimerization of ENT1 transporter improves response rates of patients with sarcoma
Aditya Ganju, Shyam Rao, Mark A. Dickson, Robert A. Lefkowitz, Chris Thompson, Jin Cheng, Katia Manova, Adriana Haimovitz-Friedman, Gary Schwartz, Zhigang Zhang, Zvi Fuks, William D. Tap, Richard Kolesnick ASCI
Microglial GRB2 is essential for brain ventriculogenesis and cerebrospinal fluid homeostasis
Phan Q. Duy, Benjamin C. Reeves, Huanxing Sun, Xueyan Peng, Pazhanichamy Kalailingam, Garrett Allington, Evan Dennis, Le Thi Hao, Lei Wang, David Rufino-Ramos, Shujuan Zhao, Qiang Li, Neel H. Mehta, William C. Davalan, Mason Blacker, Anthony J. Piscopo, Shozeb Haider, Baojian Fan, Kedous Y. Mekbib, Shuai Shao, Carol Nelson-Williams, TuKiet T. Lam, Benjamin P. Kleinstiver, Patricia L. Musolino, Seth L. Alper, Sheng Chih Jin, Erica L. Herzog, Kristopher T. Kahle ASCI
Polycomb scaffolding subunit EED supports the SCLC neuroendocrine identity and EGFR-mutant LUAD-to-SCLC transformation
Yixiang Li, Yasmin N. Laimon, Hyeonseo Cho, Marina Vivero, Gabriel Roberti de Oliveira, Maxwell D. Seager, Andrew Delcea, Varunika Savla, Yuting Chen, Yavuz T. Durmaz, Xintao Qiu, Shweta Kukreja, Rong Li, Talal El Zarif, Wesley Lu, McKayla Van Orden, Jacob E. Berchuck, Roderick T. Bronson, Shuqiang Li, Hongbin Ji, David A. Barbie, Katerina Politi, Matthew L. Freedman, Henry W. Long, Sabina Signoretti, Matthew G. Oser ASCI
Tumor NLRP3 amplification promotes immunotherapy resistance by inhibiting STAT1 signaling and MHC class I expression
Balamayroon Theivanthiran, Nagendra Yarla, Kaylee Villarreal, Y-Van Nguyen, Mahere Rezazade Bazaz, Ernesto Pena Calderin, Linda Cao, Kyra Majors, Michael P. Plebanek, Alisha Holtzhausen, Emily Bolch, Douglas B. Johnson, Hope Uronis, John H. Strickler, Nicholas C. DeVito, Brent A. Hanks ASCI
Efferocytosis activates a DNMT3A-mediated oxidized DNA repair pathway to enable tissue resolution
Kleopatra Avrampou, Santosh R. Sukka, David Ngai, Patrick Ampomah, Xiaobo Wang, George Kuriakose, Jacob Glass, Bernhard Dorweiler, Hanna Winter, Lars Maegdefessel, Hanrui Zhang, Aaron Viny, Ira Tabas ASCI
MANF clears mutant uromodulin in human kidney organoids of autosomal dominant tubulointerstitial kidney disease
Chenjian Gu, Yili Fang, Yixuan Wang, Eric Tycksen, Gayathri Kondepati, Chuang Li, Kendrah O. Kidd, Jun Liu, Fumihiko Urano, Maria Lindahl, Anthony J. Bleyer, Srikanth Singamaneni, Zhao Sun, Ying Maggie Chen ASCI
Combined loss of histone methyltransferases GLP and G9a disrupts neural crest cell fate determination
Diana B. Voss, Emily J. Shields, Andrey Poleshko, Li Li, Jun Li, Roger Wang, Mariacristina Calcagno, Rajan Jain, Cheryl L. Smith, Jonathan A. Epstein ASCI
A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists
Warren T. Yacawych, Yi Wang, Guoxiang Zhou, Shad Hassan, Cagri Bodur, Elisabeth Walters, John G. Santinga, Frederike Sass, Martin deVaux, Stace Kernodle, Iris Wu, Jenny M. Brown, Dylan M. Belmont-Rausch, Alan C. Rupp, Abigail J. Tomlinson, Zitian Lin, Emma VanTongeren, Anna Secher, Kirsten Raun, Tune H. Pers, Randy J. Seeley, Martin G. Myers Jr. ASCI , Weiwei Qiu
Cerebellar and frontal lobe alterations in pulmonary hypertension implicate an inflammatory lung vascular/brain axis
Satoshi Okawa, Yinan Shi, Somanshu Banerjee, Yi Yin Tai, Jamal Nabhanizadeh, Stefan Guenther, Anisha N. Shah, Siyi Jiang, Timothy Kim, Yassmin Al Aaraj, Caroline Pidro, Metin Aytekin, Omolara Fatukasi, Nishita Kalepalli, Joseph M. Mettenburg, Timothy D. Girard, James T. Becker, Kathiravan Kaliyappan, Shanshan Song, Sandra Breuils-Bonnet, Steeve Provencher, Sebastien Bonnet, Theodore Huppert, Lloyd D. Harvey, S. Mehdi Nouraie, Rajkumar Savai, Dandan Sun, Soban Umar, Soni S. Pullamsetti, Stephen Y. Chan ASCI
Conserved neuronal-like and secretory programs define the spatial architecture of gastroenteropancreatic neuroendocrine tumors
Julie Karam, Samantha E. Hoffman, Amanda Garza, Dan Gui, Hannah I. Hoffman, Breanna M. Titchen, Yutaro Tanaka, Erica Pimenta, Theodora Pappa, Laura Valderrabano, Kevin Bi, Riaz Gillani, Lauren Brais, Erin Shannon, Jason L. Hornick, Jihye Park, Jennifer Chan, Eliezer M. Van Allen ASCI
Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease
Pasquale Mone, Davide Viggiano, Antonella Pansini, Maria Virginia Soldovieri, Giada Sabatelli, Valeria Visco, Gaetano Macina, Eugenio Boccalone, Michele Ciccarelli, Giuseppe Martinelli, Marco Di Mauro, Carmine Vecchione, Maria Morgante, Fahimeh Varzideh, Germano Guerra, Gaetano Santulli ASCI
B cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma
Kavita M. Dhodapkar, Antonio Matera, Alyssa M. Duffy, Azmain Taz, Renee Julia Manalo, Melinda Yushak, Ragini Kuchadkar, David H. Lawson, Madhav V. Dhodapkar ASCI
KROX20 marks sebaceous gland stem cells and regulates their differentiation to maintain skin oil balance
Yumeng Zhang, Pernelle Pulh, Michelle F. Pan, Yi He, Juanzhu Yan, Annie Li, Renée M. McKay, Lu Q. Le ASCI

JCI Insight

Publications in the last 3 months by ASCI-member corresponding authors:

Distal enhancer-insulator module of GDF6 is essential for cochlear formation
Mohammad Faraz Zafeer, Clemer Abad, Havva Ortabozkoyun, Memoona Ramzan, Guney Bademci, Maria C. Robayo, Duygu Duman, Rolen M. Quadros, Shengru Guo, Juan I. Young, Anthony J. Griswold, Channabasavaiah B. Gurumurthy, Derek M. Dykxhoorn, Katherina Walz, Mustafa Tekin ASCI
A distinct form of fat fibrosis is linked to insulin resistance in people with HIV
Diana L. Alba, Alaa Abdellatif, Moon K. Choi, Stephen M. Brown Mayfield, Thuy An T. Pham, David I. Berrios, Antonio E. Rodriguez, Marin Ewing, Tony R. Figueroa, Judy Gonzalez-Vargas, Ningyan Zhang, Zhiqiang An, Dawei Bu, Steven G. Deeks, Philipp E. Scherer, Peter W. Hunt, Suneil K. Koliwad ASCI
Druggable genome CRISPRi screen in hydrogels reveals regulators of cortactin-driven actin remodeling promoting glioblastoma invasion
Mufeng Hu, Anna Weldy, Isabella M. Lovalvo, Erin A. Akins, Saket Jain, Alexander Chang, Ankita Sati, Meeki Lad, Austin Lui, Akhil Rajidi, Ameya Kothekar, Erika A. Ding, Juan A. Oses Prieto, Pablo Estevez, Alma L. Burlingame, Sanjay Kumar, Manish K. Aghi ASCI
Mononuclear phagocyte–specific cGAS/STING targeting suppresses experimental choroidal neovascularization
Le Shi, Durgadas Cherukaraveedu, Hongkwan Cho, Kaoru Ri, Lingli Zhou, Yingxue Cao, Narendra Kale, Zhenhua Xu, Wathsala Liyanage, Rangaramanujam M. Kannan, Elia J. Duh ASCI
Acute tubular injury versus acute interstitial nephritis in the kidney precision medicine project
Jennifer A. Schaub, Rajasree Menon, Ricardo Melo Ferreira, Elizabeth Kiernan, Insa M Schmidt, Christine P. Limonte, Soumya Yennapureddy, Ying-Hua Cheng, Leal Herlitz, Avi Z Rosenberg, Joel M. Henderson, Kelly Smith, Jeffrey Hodgin, Edgar A. Otto, Gilbert Moeckel, Lloyd G Cantley, Suman Setty, Ulysses G. J. Balis, Dawit Demeke, Agnes Fogo, Andrew S Bomback, Vivette D'Agati, Isaac E. Stillman, Jose Torrealba, Allen R. Hendricks, Erika R Bracamonte, Vanessa Moreno, Pavan K Bhatraju, Amy Mottl, Frank Brosius, Bijin Thajudeen, Steven G Coca, Paul M. Palevsky, Parmjeet Randhawa, Raghavan Murugan, Laura Barisoni, Charles E. Alpers, Steven Menez, Francis P Wilson, Dennis G Moledina, Michael T Eadon, Matthias Kretzler, Jonathan Himmelfarb, Chirag R. Parikh ASCI
Excess muscle plasma membrane leak disrupts ECM content and shifts macrophage-mediated muscle repair
GaHyun Lee, Alexander J. Fitt, Ashlee M. Long, Lauren A. Vaught, Dorothy DeBiasse, Alexander R. Keeble, Jason M. Kwon, Patrick G.T. Page, Marie-Therese Daher, Michele Hadhazy, Alexander B. Willis, David Ceja Galindo, Maxwell C. McCabe, Connor Lantz, Kirk C. Hansen, Rachelle H. Crosbie, Edward B. Thorp, Alexis R. Demonbreun, Elizabeth M. McNally ASCI
Epigenomic profiling links IGF2 overexpression to anthracycline resistance in colorectal cancer organoids
Tara L Hogenson, William Phillips, Merih D Toruner, Zachry S. Poshusta, Luciana Almada, Hao Xie, Ryan M. Carr, Jenny J. Li, David L. Marks, Renzo Vera, Erik Jessen, Michael Barrett, Joleen Hubbard, Travis E. Grotz, Martin E. Fernandez-Zapico ASCI
CAR19 Tregs treat murine chronic graft-versus-host disease through immune suppression without measurable B cell cytolysis
Sujeong Jin, Michael C. Zaiken, Cameron McDonald-Hyman, Christina R. Hartigan, Sara Bolivar-Wagers, Jemma H. Larson, Yiyun Peng, Sophia Hani, Megan Riddle, Asim Saha, Angela Panoskaltsis-Mortari, Eun Ko, Yujie Zhao, Rocio Amaro Marquez, Pooja Shree Marri Baskar, Cindy R. Eide, William J. Murphy, Keli L. Hippen, Geoffrey R. Hill, Jakub Tolar, Peter T. Sage, Christopher A. Pennell, Leslie S. Kean, Bruce R. Blazar ASCI
Innate immune sensor NOD2 promotes cartilage degradation and osteoarthritis progression by stabilizing TRAF6 in chondrocytes
Yuting Wang, Song Li, Yonghui Dong, Jiaming Zhang, Jian Liu, Zhenggang Wang, Shuang Liang, Nathan Martinez, Hongxu Pu, Peng Cheng, Anmin Chen, Qing Yang, Charles Chan, Wen Jiang ASCI , Jun Xiao, Fengjing Guo, Liming Zhao
Renin cells orchestrate a neuro-endocrine microenvironment of the kidney arterial tree in health and disease
Manako Yamaguchi, Georgina Gyarmati, Liam McLaughlin, Hiroki Yamaguchi, Jason P. Smith, Lucas Ferreira de Almeida, Daisuke Matsuoka, Alexandre G. Martini, Sara M. Wilmsen, Sijie Hao, Kazuki Tainaka, Silvia Medrano, Sanjay Jain, Janos Peti-Peterdi, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez ASCI
Ampyrone is a direct agonist of human tyrosinase and a potential therapeutic for hypopigmentation disorders
Monika B. Dolinska, Yuhong A. Wang, Nathan P. Coussens, Vijay K. Kalaskar, Zuhal Eraslan, Samuel J. Grondin, Joseph Bonica, Sarah Toay, Matthew D. Hall, Min Shen, Matthew Boxer, Qiuying Chen, Steven S. Gross, Nabeel Attarwala, Yingyos Jittayasothorn, Ramakrisha P. Alur, Dhyanam Shukla, Robin Kee, Charles DeYoung, Cuilee Sha, David R. Adams, Stacie K. Loftus, Tiziana Cogliati, Yuri V. Sergeev, Jonathan H. Zippin, Brian P. Brooks ASCI
Matrikines dictate the amplitude of inflammation in smoke-related Streptococcus pneumoniae pulmonary infection
Sarah W. Robison, Jindong Li, Kristopher R. Genschmer, Liliana Viera, Jeremy B. Foote, Landon Wilson, W. Edward Swords, J. Edwin Blalock, Amit Gaggar ASCI , Xin Xu
A validated, modifiable proteomic score from the EXSCEL trial predicts cardiovascular events in diabetes
Kristin M. Corey, Maggie Nguyen, Michael Y. Mi, Megan E. Ramaker, Ilya Zhbannikov, Harald Sourij, G. Michael Felker, Naveed Sattar, Jennifer B. Green, Pamela S. Douglas, Robert E. Gerszten, Robert J. Mentz, Adrian F. Hernandez, Rury R. Holman, Bruce M. Psaty, James S. Floyd, Svati H. Shah ASCI
Noncoding RNA TY1 reverses fibrosis in systemic sclerosis by attenuating the cGAS/STING pathway
Xaviar M. Jones, Salwa Soussi, Alessandra Ciullo, Kara Tsi, Weixin Liu, Liang Li, Mario Fournier, Thassio Mesquita, Alberto Marchevsky, Nunzio Bottini, Francesco Boin, Ahmed G. Ibrahim, Eduardo Marbán ASCI
Human Y chromosome pan-organ mapping reveals progressive mosaic loss from normal to cancer
Arkadiusz Gertych, Huihui Ye, Xingyu Chen, Eric Vail, V Krishnan Ramanujan, Lauren Brady, Lawrence D True, Peter Nelson, Peter Carroll, Dan Theodorescu ASCI
Local growth hormone promotes benign prostatic hyperplasia
Masaki Ryuzaki, Svetlana Zonis, Neil A. Bhowmick, Sandrine Billet, Saravana Kumar Kailasam Mani, Stephen J. Freedland, Hyung L. Kim, Vera Chesnokova, Shlomo Melmed ASCI
Urinary YKL-40 as a diagnostic biomarker for cystinosis
Jason H. Greenberg, Serena D. D Souza, Heather R. Thiessen Philbrook, Wassim Obeid, Avi Z. Rosenberg, Elena Levtchenko, Koenraad Veys, Susan L. Furth, Chirag R. Parikh ASCI
Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation
Lun Li, Rhonda Lightle, Bader Ali, Georgeio Sader, Robert Shenkar, Sean P. Polster, Douglas A. Marchuk, Jan-Karl Burkhardt, Issam A. Awad, Mark L. Kahn ASCI
Plasma proteins associated with chronic graft-versus-host disease organ involvement
Stephanie J. Lee ASCI , Corey Cutler, Ningxin Ma, Timothy W. Randolph, George L. Chen, Joseph Pidala, Betty K. Hamilton, Carrie L. Kitko, Sally Arai, Najla El Jurdi, Lynn Onstad, Motoko Koyama, Catherine J. Lee, Sophie Paczesny, Geoffrey R. Hill
E-cigarette exposure triggers distal lung cell injury, persistent lung stress response, and antiviral immune suppression
Tanner C. Rivera, Kelly S. Schweitzer, Christina F. Cornell, Jordan M. Nall, Nicholas Egersdorf, Courtney Moeder, Riley A. Cooney, Eszter K. Vladar, Steve D. Groshong, Gregory P. Downey, James P. Bridges, Richard Bowen, Hong Wei Chu, Irina Petrache ASCI
Phase III trial of sodium dichloroacetate for pyruvate dehydrogenase complex deficiency in children
Peter W. Stacpoole ASCI , Jose E. Abdenur, Jirair K. Bedoyan, Lorenzo D Botto, Gregory M. Enns, Marni J. Falk, Rebecca D. Ganetzky, Cheryl L Garganta, Kevin E. Glinton, Andrea Gropman, Sharon Hamm, Eugenia Henry, Nicola Longo, Richard Neiberger, Russell P. Saneto, Fernando Scaglia, S.H. Subramony, Jerry Vockley, Richard E. Wagner
Pan-African hybridization of PfSPZ increases antigenic diversity and replicative capacity for malaria vaccine design
Lucia Pazzagli, Bethany Jenkins, Ankit Dwivedi, Asha Patil, Yonas Abebe, Tales V. Pascini, Urvashi Rai, Priya Gupta, Nastaran Rezakhani, Chakshu Gandhi, Yiwei Yang, Sudhir Kumar, Mohd Kamil, Gigliola Zanghí, Manuel Llinás, Stephen L. Hoffman ASCI , Joana C. Silva, Ashley M. Vaughan, B. Kim Lee Sim
Combined BET bromodomain and DNA methyltransferase inhibition targets critical survival pathways in transdifferentiated prostate cancer
William K. Storck, Diana Flores, Anbarasu Kumaraswamy, Zhi Duan, Shrabastee Chakraborty, Chao Zhang, Eva Rodansky, Dhruv Khokhani, Olivia A. Swaim, Karan Bedi, Raymond G. Cavalcante, Canping Chen, Faming Zhao, Ya-Mei Hu, Zheng Xia, Ryan J. Rebernick, Marcin Cieslik, Rahul Mannan, Somnath Mahapatra, Arul M. Chinnaiyan, Aaron M. Udager, Joshua A. Kuleape, Catherine R. Alumkal, Hannah N. Beck, Peter S. Nelson, Colm Morrissey, Michael C. Haffner, Leigh Ellis, Yuzhuo Wang, Joel A. Yates, Joshi J. Alumkal ASCI
177Lu-labeled DOTA-EB-RGD as a candidate for thyroid cancer therapy
Sonam Kumari, Rhitajit Sarkar, Zhantong Wang, Shilpa Thakur, Laura Abaandou, Oksana Gavrilova, Huiyan Lu, Noha Behairy, Lixin Lang, Dale Kiesewetter, Vasyl Vasko, Joanna Klubo-Gwiezdzinska ASCI
EPHA2 and WNT reciprocally regulate MAPK-dependent gene expression in a pancreatic cancer model
Shawn R. Wadia, Changyuan Hu, Siddhi Patnaik, Shreya Sridharan, Roger J. Daly, David M. Virshup ASCI , Babita Madan
Basal cell transplantation supports multilineage differentiation and restores CFTR function in ex vivo ferret airways
Kadambari Vijaykumar, Liang Ma, Kevin Chen, Liping Tang, Nikoleta Pavelkova, Elex Harris, Kajal Jadhav, Qian Li, Mohamed Hanafy, Hinnerk Schulz-Hildebrandt, Guillermo J. Tearney, Finn Hawkins, Darrell N. Kotton, Steven M. Rowe ASCI
SMURF2 inhibits autophagic control of Mycobacterium tuberculosis in macrophages
Priscila C. Campos, Kathryn C. Rahlwes, Victoria A. Ektnitphong, Beatriz R.S. Dias, Kubra F. Naqvi, Samuel Alvarez-Arguedas, Michael U. Shiloh ASCI
Network modeling predicts how DYRK1A inhibition promotes cardiomyocyte cycling after ischemia/reperfusion injury
Bryce C. Murillo, Alexander Young, Kaitlyn L. Wintruba, Alexander J. Eichert, Klara Siejda, Dennon Hoernig, Leigh A. Bradley, Bryana N. Harris, Catherine Zhao, MIchelle Wu, Emmanuel Deau, Mattias F. Lindberg, Laurent Meijer, Jeffrey J. Saucerman, Matthew J. Wolf ASCI
Stabilization of the PP2A-B56α complex overcomes venetoclax-azacitidine resistance by impairing OXPHOS in AML
Silvia Romero-Murillo, Irene Peris, Anna Maria Lucianò, Nerea Marcotegui, Carmen Vicente, Brian Tran, Kelsey Barrie, Caitlin M. O'Connor, Andrea Torres-López, Maria C. Mateos, Maria L. Cayuela, Victoriano Mulero, Joaquín Fernández-Irigoyen, Enrique Santamaría, Maria D. Odero, Goutham Narla ASCI
PTHrP induces breast cancer bone metastases via microbial-dependent expansion of TNF/IL-17–producing T cells
Nand K. Roy, Subhashis Pal, Hamid Y. Dar, Sanchiti Patil, M. Neale Weitzmann, Roberto Pacifici ASCI
Patient-derived neomorphic SEPTIN6 mutations induce hematopoietic stem cell senescence underlying congenital neutropenia and myelodysplasia
Safa F. Mohamad, Meaghan McGuinness, Yu Zhou, Xin Jiang, Gabriele Casirati, Adele Mucci, Sara Canovas Nunes, Akiko Shimamura, Pietro Genovese, David A. Williams ASCI