Lida Hariri, MD, PhD, is a physician-scientist and Associate Professor of Pathology at Massachusetts General Hospital (MGH), Harvard Medical School. She obtained her MD/PhD at the University of Arizona in 2009, with her PhD in Biomedical Engineering focused on multimodal optical imaging for early cancer detection. She subsequently completed pathology residency and fellowship at MGH. In 2013, she joined the faculty at MGH, Harvard Medical School. She is a member of the Fleischner Society, fellow of the American Thoracic Society (ATS) and College of American Pathologists (CAP), and has held numerous ATS committee roles. 

Dr. Hariri’s research interests include bench-to-bedside development, translation and clinical application of high-resolution optical imaging in pulmonary disease. Her laboratory is particularly interested in endobronchial optical coherence tomography (EB-OCT) for early detection, diagnosis, and monitoring of interstitial lung disease (ILD), interstitial lung abnormalities (ILA), inhalational lung disease, long COVID, and lung cancer. Her laboratory established EB-OCT for early, microscopic ILD diagnosis, demonstrating high accuracy, sensitivity, and specificity compared to histopathology in patients with otherwise low-confidence diagnosis. Her laboratory also showed that amongst individuals with incidental ILA on CT, EB-OCT-detected microscopic high-risk fibrotic features were predictive of subsequent progression and development of symptomatic ILD. Her laboratory has conducted studies identifying small airways abnormalities as a pathologic feature of early IPF and constrictive bronchiolitis associated with heavy vaping. Currently, her laboratory is investigating EB-OCT-detected microscopic collagen orientation as a prognostic biomarker of ILD progression, repeat EB-OCT imaging for disease monitoring in IPF and long COVID, and incorporation of artificial intelligence for automated classification and quantification of microscopic disease. She is PI on multiple NIH R01 and Department of Defense awards. Many trainees in Dr. Hariri’s lab have received recognition for their impactful research, including highlights as Emerging Investigators by the ATS and NIH Career Development Awards.