Matt Sampson is the Warren E. Grupe Chair of Pediatric Nephrology at Boston Children’s Hospital, Associate Professor of Pediatrics at Harvard Medical School, Associate Member of the Broad Institute, and Research Nephrologist at Brigham & Women’s Hospital. He received his BS in Cell and Molecular Biology from Duke University, MD from University of Virginia, and a Master’s in Clinical Epidemiology from the University of Pennsylvania. He completed his residency and fellowship at Chidlren’s Hospital of Philadelphia. Matt co-chairs the Genetics and Genomics Working Group of the Nephrotic Syndrome Study Network (NEPTUNE) and the Basic Science and Translational Research Committee of the International Society of Glomerular Disease. The goals of his research program are to map the genomic determinants of nephrotic syndrome, particularly from a non-Mendelian perspective, and to discover the molecular, mechanistic, and clinical consequences of them when they are found. They have a specific focus on pediatric nephrotic syndrome and APOL1 mediated FSGS (AMFSGS). When present, his lab uses established methods from statistical genetics and computational biology to create high-quality variant call sets, perform genome-wide association, expression quantitative trait loci, and multiomic studies, and then uses genetic epidemiology to contextualize disease-associated variants. They use functional genomics approaches to experimentally characterize candidate genes and variants. When existing methods are not sufficient, they develop their own. His expertise in kidney genomics and the translation of genomic discovery to genomic medicine is recognized nationally and internationally, with multiple independent grants from the NIDDK since 2015 and leadership roles in international organizations and consensus groups. Matt has a strong record of mentorship, having trained 4 MD PhDs, 5 MDs, and 6 MS and PhDs since 2014. Finally, the Sampson Lab is committed to creating user friendly, publicly available databases to share genomic information, and have created nephqtl2.org and apol1portal.org to do this.