Steven E. Mansoor, M.D./Ph.D., is a physician-scientist in the Department of Chemical Physiology and Biochemistry (CPB) and the Knight Cardiovascular Institute (KCVI) at Oregon Health & Science University (OHSU). He received a bachelor’s degree from Reed College where he majored in biochemistry and molecular biology. He then received a combined M.D./Ph.D. degree from OHSU before fast-tracking through internal medicine residency into a combined clinical cardiology/research fellowship at OHSU. In addition to running a basic science research program, Dr. Mansoor is an active clinical cardiologist treating patients with cardiovascular disease. The Mansoor Lab uses structure/function studies to explore and define the molecular pharmacology of ligand-gated ion channels and G-protein coupled receptors in order to then use in silico, structure-based drug design to develop novel small-molecules capable of selectively modulating the function of these receptors. His research vision spans from studying molecular ligand/receptor interactions at the laboratory bench, to development of novel small-molecule pharmacologic therapies, and to ultimately treating patients with cardiovascular diseases at the bedside. 

In addition to clinical medicine and research, Dr. Mansoor is passionate about the mentoring and education of future scientists and physician-scientists. He has served on the OHSU M.D./Ph.D. committee since 2018. He is a member of his department’s diversity equity and inclusion (DEI) committee formed in early 2022. Since 2018, he has had high school students, college students, and OHSU employees shadowing him in general cardiology clinic in order to give under-represented and underprivileged applicants an introduction into medicine and science to ultimately mentor them into M.D./Ph.D. or physician-scientist pathways.

Dr. Mansoor has received an NIH Director’s New Innovator Award (DP2), an NIH Pathway to Independence Award (K99/R00) from the National Heart, Lung, and Blood Institute (NHLBI), an American Society for Clinical Investigation (ASCI) Young Physician-Scientist Award, and a Gilead Research Scholars Award in Cardiovascular Comorbidities.