Dr. Ojo's research work consists of the clinical investigation of the risk factors, access and outcomes of kidney and pancreas transplantation and kidney failure in non-renal solid organ transplantation. Additional areas of investigation include hypertensive nephrosclerosis in blacks and…
more progression of chronic kidney disease. Dr. Ojo’s research in HLA identical living donor renal transplant recipients provided concrete clinical evidence that innate immunologic variables are predominantly responsible for inferior results of kidney transplantation in blacks. Dr. Ojo's research team has also shown the impact of chronic kidney disease in heart, lung and liver transplant recipients. Ongoing investigations include clinical trials of steroid-free, calcineurin minimization regimen in black de novo kidney transplant recipients, cohort studies of cardiovascular disease and progression of renal failure in patients with chronic kidney disease and genetic determinants of susceptibility to calcineurin inhibitor nephrotoxicity in non-renal transplant recipients. Strategies to evaluate and improve the potential supply of living and deceased organ donors are also being investigated in population-based and prospective clinical studies.
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