ASCI / Young Physician-Scientist Awards, 2024
The Young Physician-Scientist Awards (YPSA) recognize physician-scientists who are early in their first faculty appointment and have made notable achievements in their research.
About the awardee
Michael Honigberg, MD, MPP is a cardiologist-investigator in the Cardiology Division at Massachusetts General Hospital (MGH), Assistant Professor of Medicine at Harvard Medical School, and Associate Member of the Broad Institute of MIT and Harvard. He received his MD from Harvard Medical School and MPP from the Harvard Kennedy School of Government, trained in internal medicine at Brigham and Women’s Hospital, and completed clinical and research fellowship in cardiovascular medicine at MGH.
Dr. Honigberg’s research combines epidemiology, human genetics, multi-omics approaches, and imaging to (1) elucidate sex-specific risk factors for cardiovascular disease in women and their underlying mechanisms, (2) improve cardiovascular risk prediction and allocation of existing and novel preventive therapies, and (3) define precision strategies for cardiovascular risk reduction in high-risk populations. His recent work has focused on defining the cardiovascular consequences of preeclampsia and premature age of menopause onset, including identification of germline and somatic genomic factors that contribute to heightened cardiovascular risk in affected women. He recently led the largest genome-wide association study to date of preeclampsia and gestational hypertension (Nature Medicine 2023), yielding new insights into disease mechanisms and shared genetic risks with cardiovascular disease. In addition, he studies the cardiovascular consequences of clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of blood stem cells harboring pre-leukemic driver mutations. His research program is supported by a K08 award from the National Heart, Lung, and Blood Institute, a career development award from the American Heart Association, and additional grants from the American Heart Association and Patient-Centered Outcomes Research Institute. Dr. Honigberg is the recipient of the Jeremiah Stamler Award from the Northwestern Cardiovascular Young Investigators’ Forum and the 2023 Douglas P. Zipes Distinguished Young Scientist Award from the American College of Cardiology.