ASCI / Young Physician-Scientist Awards, 2023

Danny E. Miller, MD, PhD is an Assistant Professor at the University of Washington in the Departments of Pediatrics, Division of Genetic Medicine, and Laboratory Medicine & Pathology. Danny completed his medical and graduate work at the University of Kansas, in affiliation with the Stowers Institute for Medical Research, followed by a combined residency in Pediatrics and Medical Genetics at Seattle Children’s Hospital and the University of Washington. The mission of the Miller lab is to reduce the burden of undiagnosed genetic diseases on patients and their families by improving the efficiency and effectiveness of genetic testing, and to better understand human genetic disease through the identification and characterization of novel disease-causing variation. To do this, the Miller lab uses new technologies, such as long-read DNA and RNA sequencing, to improve the efficiency and effectiveness of genetic testing and to identify and characterize novel disease-causing genetic variation. The lab is actively working to develop new long-read sequencing-based clinical tests to increase the rate of genetic diagnosis and shorten the time required to make a genetic diagnosis. Danny first began using long-read sequencing during his graduate training at the University of Kansas and the Stowers Institute for Medical Research under the mentorship of R. Scott Hawley, and later continued to gain expertise in the field while performing research in Evan Eichler’s lab during his combined residency in Pediatrics and Medical Genetics at Seattle Children’s Hospital and the University of Washington. Clinically, Danny sees patients in general genetics clinic as well as skeletal dysplasia clinic at Seattle Chidlren's Hospital.