Dr. Takebe serves as director for commercial innovation within the Center for Stem Cell and Organoid Research and Medicine (CuSTOM) at Cincinnati Children’s. He is also on the faculty within the Institute of Research at Tokyo Medical and Dental University in Japan. Dr. Takebe's team has been successful in designing complex miniature organs in a dish from pluripotent stem cells, for example, by integration of vascular, mesenchymal and immune components into human liver organoids. Most notably, while studying early liver development, his team engineered human stem cells into multi-organs composed of hepato-biliary-pancreatic tissue with interconnected structures. Dr. Takebe has been honored with the Japan Academy Medal and the Robertson Stem Cell Investigator Award from The New York Stem Cell Foundation.