Dr. Ethan Basch is a practicing oncologist and Director of Cancer Outcomes Research at the University of North Carolina, where he is Professor of Medicine and Professor of Public Health. His research group leads national and international efforts developing, testing, and implementing patient-reported outcome (PRO) questionnaires and technology platforms, and setting methodological standards for the use of PROs in oncology. His group established that up to half of patients’ symptoms go undetected during cancer treatment and clinical trials, and that patient engagement and patient-reported outcome questionnaires substantially improve detection. His team determined that integrating web-based patient-reported symptoms into oncology practice improves clinical outcomes and reduces health service utilization. His team created a system for the National Cancer Institute (NCI) to collect patient-reported side effects during cancer drug development called the ‘PRO-CTCAE,’ which is now being integrated widely in cancer clinical trials. Dr. Basch is also involved in efforts to bring PROs into comparative effectiveness research and quality improvement. He is a member of the Board of Scientific Advisors for the U.S. National Cancer Institute (NCI), the Methodology Committee of the Patient-Centered Outcomes Research Institute (PCORI), and is an Associate Editor at JAMA. His overall objective is to develop and implement systematic approaches that better inform clinicians and researchers about the patient experience, to improve quality of care delivery.