Samir Parikh is Chief of Nephrology, Professor of Internal Medicine and Pharmacology, holder of the Robert Tucker Hayes Distinguished Chair in Nephrology in honor of Floyd Rector, Jr., and holder of the Ruth W. and Milton P. Levy, Sr., Chair in Molecular Nephrology at the University of Texas Southwestern. Dr. Parikh graduated magna cum laude from Harvard College and received the Founder’s Medal from Vanderbilt University School of Medicine for highest academic standing. He completed residency and nephrology fellowship at Beth Israel Deaconess Medical Center and Harvard Medical School where he rose to the rank of Professor of Medicine. Dr. Parikh has served as principal investigator on research grants from the National Institutes of Health, American Society of Nephrology, American Heart Association, and American Diabetes Association. Dr. Parikh's mentorship and teaching have been recognized with awards from Harvard Medical School and BIDMC. His research is focused on the discovery and translation of molecular mechanisms underlying sepsis and acute kidney injury. Dr. Parikh has proposed that the host vascular response to severe infections may underlie lethal disease manifestations in a way that can be measured, predicted and therapeutically targeted. His group is evaluating the Tie2 receptor on vascular endothelium as a candidate pathway. Studies into mechanisms of acute kidney injury have implicated renal deficiency of NAD+ as a potential causal factor.  This work bridges the arenas of aging research, molecular metabolism, and physiology: NAD+ augmentation may fortify metabolically active organs against diverse acute stressors. For these advances, Dr. Parikh has received NIH/NHLBI’s 2018 Outstanding Investigator Award, the Interurban Clinical Club’s 2018 William Osler Award, and the 2019 Donald Seldin Young Investigator Award from the American Society of Nephrology and the American Heart Association.