Christine Iacobuzio-Donahue is an Attending Physician in Pathology, Associate Director of Translational Research for the David M. Rubenstein Pancreatic Cancer Research Center, and Director of the Rapid Autopsy Program at Memorial Sloan Kettering Cancer Center in NYC. She is internationally known for her work on the genetics of pancreatic cancer including the clonal evolution and timing of pancreatic cancer from its inception through metastasis to distant sites. The majority of her time is devoted to leading an NIH funded laboratory focused upon the genetics and distinct evolutionary dynamics of clonal evolution in a spectrum of solid tumors using methods such as next generation sequencing, transgenic mouse models and experimental evolution.