Photo: Benjamin Z. Leder, MD
Benjamin Z. Leder, MD
Year elected: 2011
Current membership category: Active
Massachusetts General Hospital and Harvard Medical School
Endocrine Unit, THR 1051
50 Blossom St
Boston, MA 02114
United States of America
Phone: 617 726-6723
Facsimile: 617 726 1703

Biographical statement

Our research team is focused on investigating the hormonal influences of bone metabolism. Using clinical research techniques ranging from smaller-scale physiological studies and larger clinical trials, we further aim to use this better understanding of the hormonal regulation of bone to improve the treatment of osteoporosis in older men and women. Our group helped demonstrate selective roles for androgens and estrogen in regulating bone metabolism in men and has defined the potential of aromatase inhibition to stimulate endogenous androgen production in older men with hypogonadism. We also continue to explore the relative efficacy of antiresorptive and anabolic strategies in the treatment of osteoporosis and the potential of newer antiresorptive agents to augment the anabolic potential of parathyroid hormone in humans.

Institutional affiliations

Harvard Medical School, Massachusetts General Hospital (Primary)
Dennis A. Ausiello, MD is the representative at this institution.


Internal Medicine