Photo: Paul A. Goepfert, MD
Paul A. Goepfert, MD
Year elected: 2010
Current membership category: Senior
University of Alabama at Birmingham
908 20th Street South
CCB 328
Birmingham, AL 35294
United States of America
Phone: 205-975-5667
Facsimile: 205-975-6027

Biographical statement

Dr. Goepfert has concentrated his research efforts into understanding the characteristics of HIV-specific CD8+ T cells that impact upon control of viral replication, and how virus fitness may be impaired when virus is forced to escape certain T cell responses. Part of this work includes a better understanding of the quality of CD8+T cells that are associated with improved HIV-1 control and disease outcome. His research also focuses on studying immune responses to epitopes derived from the translation of alternative HIV-1 reading frames. These so called cryptic epitopes can be synthesized from both sense and anti-sense RNA transcripts and may represent a potential target for vaccine directed immune responses. All of his work has had direct relevance to our understanding of T cell immunopathogenesis of AIDS, and how vaccines that stimulate T cells should be designed to have maximum impact upon the virus.

Institutional affiliations

University of Alabama at Birmingham School of Medicine (Primary)
Steven M. Rowe, MD, MSPH is the representative at this institution.


Infectious Disease