Photo: Marcel A. Behr, MD, MSc
Marcel A. Behr, MD, MSc
Year elected: 2010
Current membership category: Senior
McGill University Health Centre
Division of Infectious Diseases and Medical Microbiology
1001 boul Décarie
Montreal, PQ H4A 3J1
Canada
Phone: 514 934-1934 x42815
Facsimile: 514 934-4476

Biographical statement

Our laboratory is interested in the epidemiology and pathogenesis of mycobacterial infections. Using genetic and genomic methods, we explore host and bacterial determinants of infection and disease due to M. tuberculosis (the cause of TB) and M. avium paratuberculosis (the cause of paratuberculosis and a hypothesized microbial contributor to Crohn’s disease). Previous and ongoing work on TB include determining the basis for virulence attenuation of M. bovis BCG strains and understanding how closely related members of the M. tuberculosis are tropic for different hosts. Work on M. avium involves understanding the bacterial basis for increased virulence among pathogenic clones of this species and detailing the role of the host receptor NOD2/CARD15 in initiating innate and adaptive immune responses during mycobacterial infection. The ultimate goal of these avenues of investigation is an improved vaccine against mycobacterial diseases, especially TB, and a clearer understanding of whether mycobacterial infection contributes to the pathogenesis of human inflammatory bowel disease.

Institutional affiliations

McGill University Faculty of Medicine (Primary)
Brent Richards, MD, MSc is the representative at this institution.

Specialties

Internal Medicine