675 Charles Young Dr
Los Angeles, CA 90095
United States of America
Honors and awards
Dr. Tontonoz is Professor of Pathology and Laboratory Medicine at the University of California, Los Angeles. He received his undergraduate degree in molecular biology and biochemistry from Wesleyan University and his M.D. and Ph.D. degrees from Harvard Medical School. He carried out his postdoctoral training at the Salk Institute and completed his residency training in pathology at the University of California, San Diego. Dr. Tontonoz’s laboratory studies the regulation of gene expression by nuclear receptors and the relationship of these signaling pathways to human diseases. Obesity, diabetes, and cardiovascular disease are the leading causes of morbidity and mortality in industrialized societies. The common thread that links these disorders is dysregulation of lipid metabolism. The long-term goal of Dr. Tontonoz’s research is to understand the mechanisms whereby lipids control gene expression and impact the development of metabolic disease. Dissection of these pathways is advancing our understanding of basic mechanisms that control metabolism and highlighting new opportunities for therapeutic intervention. Dr. Tontonoz is a member of the National Academy of Sciences and the American Association of Physicians. He is the recipient of the Jeffrey M. Hoeg Research Award from the American Heart Association, and the Gerald D. Auerbach and Richard. E. Weitzman Awards from the Endocrine Society. He serves on the editorial boards of The Journal of Clinical Investigation, eLife, and Genes & development, and is Editor in Chief of Molecular and Cellular Biology.
University of California, Los Angeles, David Geffen School of Medicine (Primary)
Kalyanam Shivkumar, MD, PhD is the representative at this institution.