Andrew R. Marks, MD
Year elected: 1995
Current membership category: Senior
Honors and awards
ASCI | Stanley J. Korsmeyer Award (2010) In recognition of his discoveries that rapamycin inhibits coronary artery stent restenosis, and the role of leaky ryanodine receptor/calcium release channels in heart failure, cardiac arrhythmias and muscular dystrophy.
National Academy of Sciences (2005)
American Academy of Arts & Sciences (2005)
National Academy of Medicine (2004)
The Marks lab is devoted to improving basic understandings of mechanisms that regulate calcium dependent signals including muscle contraction and cell growth. In particular the lab focuses on the structure/function relationships of ion channel macromolecular complexes including the ryanodine receptor/ calcium release channel (RyR) and the IP3 receptor. The lab employs a wide range of techniques including molecular and cell biology, confocal calcium imaging, structural biology, muscle physiology, and generates genetically altered animal models of human diseases to test hypotheses.
Columbia University College of Physicians & Surgeons (Primary)